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Computational Biology: From Genotype to Phenotype – Teresa Przytycka, NIH Scientist

>>My name is Teresa Przytycka, and I am a senior investigator here at National Center for Biotechnology Information. My group is a purely computational group. We don’t do any wet lab experiments, but rather we do experiment with computers. We collaborate a lot with experimental biologists here at NIH, and actually one of the main […]

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Forensic Anthropology 2011 : 10 : Population Genetics pt.1

[ Music ]>>My training was in human population genetics. And I started working with DNA polymorphisms in the early 1980’s to study humans for a variety of reasons. And became involved in the late 80’s and early 90’s when DNA started being introduced into court as an expert witness. And I testified in many different […]

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Forensic Anthropology 2011 : 11 : Population Genetics pt.2

[ Music ]>>G6PD also in Mediterranean climates gives resistance to malaria– the Duffy blood group. The blood group molecule on the surface of the red cell is the molecule used for vivax malaria to infect the red cell. And so Duffy null is essentially fixed in Equatorial Africa. Not in Southern Africa. The Kwazan do […]

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Forensic Anthropology 2011 : 12 : Population Genetics pt.3

[ Music ]>>Start off with some basic rules of probability. You should all know these even intuitively if you don’t know them from mathematics. But if you’ve got mutually exclusive events, their probabilities if you want one or the other, don’t care, is the sum. If you got events that are not mutually exclusive and […]

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Pedigree Analysis – Part 1: Autosomal Inheritance Patterns

Pedigree analysis – What are the patterns of autosomal inheritance? What’s the probability of inheriting certain genetic disorders? Pedigree analysis is usually quite helpful in answering this question. Fortunately, a thorough understanding of human genetics isn’t required to do so. Usually, an overview of classical hereditary suffices. We’d like to provide you with this overview […]

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